Role of enterobacteria and HLA-B27 in spondyloarthropathies: studies with transgenic mice.

Article

Role of enterobacteria and HLA-B27 in spondyloarthropathies: studies with transgenic mice.

Annals of the rheumatic diseases - 1 Jun 1990

Nickerson C L, Luthra H S, David C S

Abstract excerpt

Several MHC (major histocompatibility complex) genes are associated with increased incidence of disease. The strongest association is between the class I gene, HLA-B27, and ankylosing spondylitis (AS). HLA-B27 is also highly associated with Reiter's syndrome. As not all subjects with HLA-B27 deve...

Topics

Animals
Arthritis
Enterobacteriaceae Infections
Genes, MHC Class I
Genes, MHC Class II
Genetic Predisposition to Disease
HLA-B27 Antigen
Mice
Mice, Transgenic
Spinal Diseases

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