Chronic myeloid leukemia: why does it evolve from chronic phase to blast transformation?

Abstract excerpt

Clinically chronic myeloid leukemia is a biphasic or triphasic disease that is usually diagnosed in the initial 'chronic', 'indolent' or 'stable' phase and then spontaneously evolves after some years into an advanced phase. This advanced phase can sometimes be subdivided into an earlier accelerated phase and a later blast phase or blast transformation--in about one-half of patients the chronic phase transforms...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blast Crisis
• Share to Cytogenetics
• Share to Cytokinesis