Article
Domain structure of phage P4 alpha protein deduced by mutational analysis.
Journal of bacteriology - 1 Aug 1995
Ziegelin G, Linderoth N A, Calendar R, Lanka E
Abstract excerpt
Bacteriophage P4 DNA replication depends on the product of the alpha gene, which has origin recognition ability, DNA helicase activity, and DNA primase activity. One temperature-sensitive and four amber mutations that eliminate DNA replication in vivo were sequenced and located in the alpha gene. Sequence analysis of the entire gene predicted a domain structure for the alpha polypeptide chain (777 amino acid...
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