Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potential biomarkers in predicting progression of epithelial hyperplastic lesions of the larynx.

Acta oto-laryngologica. Supplementum - 1 Jan 1997

Gallo O, Franchi A, Chiarelli I, Porfirio B, Grande A, Simonetti L, Bocciolini C, Fini-Storchi O

Abstract excerpt

Factors contributing to malignant transformation of laryngeal pre-neoplastic lesions remain largely unknown. Potential etiologic factors may be related to a genetically controlled sensitivity to environmental carcinogens. In this study, we investigated bleomycin-induced chromosome fragility in 15 patients with laryngeal keratoses who experienced a malignant transformation of pre-neoplastic lesions during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to Case-Control Studies

Share to Cell Transformation, Neoplastic

Share to Epithelium

Share to Genes, p53

Share to Immunohistochemistry

Source

Identifiers

PMID: 9197477
DOI: 10.3109/00016489709124030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potential biomarkers in predicting progression of epithelial hyperplastic lesions of the larynx.PMID 9197477Read ↗

Laryngeal dysplasia: aetiology and molecular biologySemantic proximity Read ↗

3p21, 5q21, 9p21 and 17p13 allelic deletions accumulate in the dysplastic spectrum of laryngeal carcinogenesis and precede malignant transformation.Semantic proximity Read ↗

Molecular markers in dysplasia of the larynx: expression of cyclin-dependent kinase inhibitors p21, p27 and p53 tumour suppressor gene in predicting cancer risk.Semantic proximity Read ↗

The role of chromosomal aberrations in premalignant and malignant lesions in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Genetic characterization of vocal fold lesions: leukoplakia and carcinoma.Semantic proximity Read ↗

Biologic correlates of a biochemoprevention trial in advanced upper aerodigestive tract premalignant lesions.Semantic proximity Read ↗

Alteration of p53 gene structure and function in laryngeal squamous cell cancer.Semantic proximity Read ↗

Genomic instability and tumor-specific DNA alterations in oral leukoplakias.Semantic proximity Read ↗

3p14 and 9p21 loss is a simple tool for predicting second oral malignancy at previously treated oral cancer sites.Semantic proximity Read ↗

Malignant transformation of recurrent respiratory papillomatosis associated with integrated human papillomavirus type 11 DNA and mutation of p53.Semantic proximity Read ↗

Chromosome instability in lymphocytes: a potential indicator of predisposition to oral premalignant lesions.Semantic proximity Read ↗

Molecular screening of oral precancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.