Article
Genomic instability and tumor-specific DNA alterations in oral leukoplakias.
European journal of oral sciences - 1 Jun 2009
Tanić Nasta, Tanić Nikola, Milasin Jelena, Vukadinović Miroslav, Dimitrijević Bogomir
Abstract excerpt
Leukoplakias, clinically identifiable premalignant lesions, often precede oral squamous cell carcinoma (OSCC). Identification of leukoplakias that have the potential for transformation to malignancy is a key clinical problem. The aim of this study was to assess genomic instability, and to detect tumor-specific genomic alterations, in leukoplakias. Genomic instability was analyzed by comparing the DNA fingerprints...
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