Article
Mathematical models of immune-induced cancer dormancy and the emergence of immune evasion
25 Jun 2013
Abstract excerpt
Cancer dormancy, a state in which cancer cells persist in a host without significant growth, is a natural forestallment of progression to manifest disease and is thus of great clinical interest. Experimental work in mice suggests that in immune-induced dormancy, the longer a cancer remains dormant in a host, the more resistant the cancer cells become to cytotoxic T-cell-mediated killing. In this work,...
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