Article
Apolipoprotein E gene and sporadic frontal lobe dementia.
Neurology - 1 Jun 1997
Stevens M, van Duijn C M, de Knijff P, van Broeckhoven C, Heutink P, Oostra B A, Niermeijer M F, van Swieten J C
Abstract excerpt
The apolipoprotein E gene has been associated with various types of dementia. We studied the connection between the APOE gene and the risk and onset of disease in 34 patients with clinically diagnosed frontal lobe dementia (FLD) derived from a population-based study in the Netherlands. A significant increased risk of FLD (odds ratio, 4.9; 95% CI, 1.1-20.1) was found for the apoE4E4 genotype when adjusting for...
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