Article
Evolution of hepatitis C virus quasispecies in mothers and infants infected through mother-to-infant transmission.
Journal of hepatology - 1 May 1997
Ni Y H, Chang M H, Chen P J, Lin H H, Hsu H Y
Abstract excerpt
BACKGROUND/AIMS: Two mother-infant pairs (Pair H and P) were studied to determine the evolution of hepatitis C virus (HCV) quasispecies. METHODS: Eight clones of the hypervariable region of HCV cDNA from the infants' sera sampled at the age of 3 months, 1, 2, and 3 years and the time-corresponding maternal sample were also sequenced. The sequences were analyzed by the nucleotide diversity, substitution rate, and...
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