Article
Molecular evolution of HCV genotype 2c persistent infection following mother-to-infant transmission.
Archives of virology - 1 Jan 2000
Rapicetta M, Argentini C, Spada E, Dettori S, Riccardi M P, Toti M
Abstract excerpt
The molecular evolution of HCV 2c in a case of vertical transmission was studied by comparing the virus quasispecies in the sera from the mother and from the child in a two-year follow-up. The positivity of HCV-RNA since the delivery accounted for an in-utero infection. The Core-E1 genome region (nt 928-1225) was amplified by polymerase chain reaction (PCR) from serum samples collected at delivery and at 3, 9, 18...
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