Article
Evolution of the E2 region of hepatitis C virus in an infant infected by mother-to-infant transmission.
Journal of medical virology - 1 Aug 2001
Sitia G, Cella D, De Mitri M S, Novati R, Foppa C U, Perackis K, Bianchi C, Lazzarin A, Morsica G
Abstract excerpt
To demonstrate vertical transmission of hepatitis C virus from an HCV infected woman and to assess the evolution of HCV quasispecies in the infant, the variable E2 region was analyzed in one mother-infant pair at birth and in serial samples from the infected baby. Sequence analysis of the E2 region obtained by means of direct sequencing of PCR products of mother-infant pair at birth, showed that the sequence of...
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