Article
Sex chromosome determination in extragonadal teratomas by interphase cytogenetics: clues to histogenesis.
Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association - 1 Jan 2000
Wagner H, Baretton G B, Schneiderbanger K, Nerlich A, Bise K, Löhrs U
Abstract excerpt
Teratomas are neoplasms that are composed of tissues from all three germinal layers. The exact histogenetic origin of teratomas, however, is still controversial. In order to gain more insight into histogenesis of extragonadal teratomas (EGTs), the gonosomal status in 13 congenital EGTs was studied by means of interphase cytogenetics using nonradioactive in situ hybridization (NISH) with centromere-specific DNA...
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