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Article

No recurrent structural abnormalities apart from i(12p) in primary germ cell tumors of the adult testis.

Genes, chromosomes & cancer - 1 Oct 1995

van Echten J, Oosterhuis J W, Looijenga L H, van de Pol M, Wiersema J, te Meerman G J, Schaffordt Koops H, Sleijfer D T, de Jong B

Abstract excerpt

Malignant transformation may be caused by gene deregulation resulting from specific chromosomal rearrangements, by amplification, by mutations in proto-oncogenes, by loss of tumor suppressor genes, or a combination of these. We investigated the role of numerical and structural chromosomal abnorma...

Topics

Adolescent
Adult
Cell Transformation, Neoplastic
Chromosome Aberrations
Chromosome Disorders
Chromosome Mapping
Chromosomes, Human, Pair 12
Genes, Tumor Suppressor
Germinoma
Humans
Isochromosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Karyotyping

Male

Mutation

Proto-Oncogenes

Testicular Neoplasms

Source

Identifiers

PMID: 8527395
DOI: 10.1002/gcc.2870140208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8527395-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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No recurrent structural abnormalities apart from i(12p) in primary germ cell tumors of the adult testis.PMID 8527395Read ↗

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