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Article

Cytogenetic Analysis of Childhood Endodermal Sinus Tumors: A Pediatric Oncology Group Study

1 Jan 1994

Abstract excerpt

Most adult germ cell tumors have a consistent cytogenetic abnormality, i(12p), and are aneuploid. Many pediatric germ cell tumors are biologically distinct from their adult counterparts, particularly endodermal sinus tumors (ESTs) of young children. We report cytogenetic and ploidy analysis of nine ESTs involving children under 3 years of age (four extragonadal and five testicular). Structural abnormalities were...

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PMID: 7971587
DOI: 10.3109/15513819409023342

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