Article
Premeiotic origin of teratomas: is meiosis required for differentiation into mature tissues?
Cell cycle (Georgetown, Tex.) - 1 Nov 2005
Zhuang Zhengping, Devouassoux-Shisheboran Mojgan, Lubensky Irina A, Tavassoli Fattaneh, Vortmeyer Alexander O
Abstract excerpt
By virtue of meiotic cell division, primordial germ cells with heterozygous alleles develop into postmeiotic germ cells with homozygous alleles. Female and male germ cells may develop tumors--so-called teratomas--with a unique coexistence of a variety of histological elements from all three embryonic germ layers. In particular, mature teratomas consist exclusively of developmentally mature tissues whereas...
Topics
Join the communities discussing this publication.
