[Structure of the retinoic acid receptor and its functional analysis using a mutated receptor].

Article

[Structure of the retinoic acid receptor and its functional analysis using a mutated receptor].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1998

Kakizuka A

Abstract excerpt

RA shows a variety of actions including the teratogenicity at pharmacological doses, but its physiological roles remain unclear. Recently, receptors for RA, RARs, have been identified and shown to belong to the nuclear receptor superfamily. We introduced a mutation, which was originally identifie...

Topics

Amino Acid Sequence
Animals
Chondrocytes
Genes, Homeobox
Mice
Mice, Knockout
Molecular Sequence Data
Mutation
Osteogenesis
Receptors, Retinoic Acid
Transgenes

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