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Article

Enhancement of bFGF export associated with malignant progression of human salivary gland cell clones.

International journal of cancer - 29 May 1997

Azuma M, Yuki T, Motegi K, Sato M

Abstract excerpt

Using 2 in vitro systems in which normal human salivary gland cells can be immortalized by transfection with SV40 DNA (NS-SV-DC), and in which a non-metastasizing human salivary gland adenocarcinoma cell clone (HSGc) can be converted to biologically aggressive and metastasizing cancer cells, we analyzed the relationship between the expression of basic fibroblast growth factor (bFGF) and malignant phenotype in...

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Identifiers

PMID: 9180161
DOI: 10.1002/(sici)1097-0215(19970529)71:5<891::aid-ijc30>3.0.co;2-8

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