Article
Effects of media conditioned by a non-metastasizing human salivary gland adenocarcinoma cell clone and metastasizing clones from salivary gland and various other tissues on the proliferation, migration and protease production of bovine aortic endothelial cells in vitro.
Cancer letters - 30 Sept 1993
Azuma M, Tamatani T, Fukui K, Yoshida H, Kamogashira T, Ogino K, Nishino N, Suzuki T, Sato M
Abstract excerpt
We demonstrate the role in tumor-associated angiogenesis of factors released into conditioned medium (CM) from in vitro human salivary gland cell clones with biological phenotypes ranging from non-metastasizing to metastasizing. A non-metastasizing human salivary gland adenocarcinoma cell clone HSGc and its subclone with metastatic potential (Gc2-100 cl-1) were employed. We also used metastasizing cell clones...
Topics
- Adenocarcinoma
- Animals
- Aorta
- Cattle
- Cell Division
- Cell Movement
- Cells, Cultured
- Clone Cells
- Collagenases
- Culture Media, Conditioned