Article
Single clonal glandular stem cells derived from human parotid glands do not attain malignant phenotype during long-term in vitro culture.
Neoplasma - 1 Nov 2021
Moon Jung-Hwa, Kim Hye-Ryun, Lim Jae-Yol, Lim Young-Chang
Abstract excerpt
Mesenchymal stem cells (MSCs) are being intensively investigated as future therapeutics for various human diseases. One of the most important challenges to the clinical application of MSCs is the possibility of malignant transformation during long-term in vitro culturing. However, there have been no reports on the tumorigenicity of salivary gland-derived MSCs following long-term in vitro culturing. Here, we...
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