Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of allelic loss of the P53 gene and tumor grade, stage, and malignant progression in bladder cancer.

International journal of urology : official journal of the Japanese Urological Association - 1 Jan 1997

Tsutsumi M, Sugano K, Yamaguchi K, Kakizoe T, Akaza H

Abstract excerpt

BACKGROUND: We examined loss of heterozygosity (LOH) of the P53 gene in bladder cancer, and investigated the role of the P53 gene on malignant progression of papillary tumors. In addition, the clonality of recurrent bladder cancer was examined. METHODS: LOH of the P53 gene was analyzed in 67 bladder cancers from 47 patients. DNA was extracted from formalin-fixed, paraffin-embedded tissues, amplified by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Disease Progression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Genes, p53

Share to Neoplasm Staging

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Translocation, Genetic

Source

Identifiers

PMID: 9179671
DOI: 10.1111/j.1442-2042.1997.tb00144.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of allelic loss of the P53 gene and tumor grade, stage, and malignant progression in bladder cancer.PMID 9179671Read ↗

Prognostic implications of p53 gene mutations in bladder tumors.Semantic proximity Read ↗

Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer.Semantic proximity Read ↗

Bladder cancer: allelic deletions at and around the retinoblastoma tumor suppressor gene in relation to stage and grade.Semantic proximity Read ↗

STAGE PROGRESSION IN TA PAPILLARY UROTHELIAL TUMORS: RELATIONSHIP TO GRADE, IMMUNOHISTOCHEMICAL EXPRESSION OF TUMOR MARKERS, MITOTIC FREQUENCY AND DNA PLOIDYSemantic proximity Read ↗

Accumulation of nuclear p53 and tumor progression in bladder cancer.Semantic proximity Read ↗

Genetic and immunophenotype analyses of TP53 in bladder cancer: TP53 alterations are associated with tumor progression.Semantic proximity Read ↗

Loss of Heterozygosity at the p53, RB, DCC and APC Tumor Suppressor Gene Loci in Human Bladder CancerSemantic proximity Read ↗

Loss of heterozygosity analysis on chromosome 5p defines 5p13-12 as the critical region involved in tumor progression of bladder carcinomas.Semantic proximity Read ↗

Evaluation of overexpression of p53 tumor suppressor protein in superficial and invasive transitional cell bladder cancer: comparison with DNA ploidy.Semantic proximity Read ↗

Analysis of genetic alterations in normal bladder urothelium.Semantic proximity Read ↗

TP53 alterations as a potential diagnostic marker in superficial bladder carcinoma and in patients serum, plasma and urine samples.Semantic proximity Read ↗

The p53 Pathway and Outcome among Patients with T1G3 Bladder TumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.