Correlation of allelic loss of the P53 gene and tumor grade, stage, and malignant progression in bladder cancer.

doi:10.1111/j.1442-2042.1997.tb00144.x

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Article

Correlation of allelic loss of the P53 gene and tumor grade, stage, and malignant progression in bladder cancer.

International journal of urology : official journal of the Japanese Urological Association - 1 Jan 1997

Tsutsumi M, Sugano K, Yamaguchi K, Kakizoe T, Akaza H

Abstract excerpt

BACKGROUND: We examined loss of heterozygosity (LOH) of the P53 gene in bladder cancer, and investigated the role of the P53 gene on malignant progression of papillary tumors. In addition, the clonality of recurrent bladder cancer was examined. METHODS: LOH of the P53 gene was analyzed in 67 blad...

Topics

Alleles
Disease Progression
Gene Deletion
Genes, p53
Humans
Neoplasm Recurrence, Local
Neoplasm Staging
Neoplasms, Second Primary
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Translocation, Genetic
Urinary Bladder Neoplasms

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Open in PubMed

Identifiers

PMID: 9179671
DOI: 10.1111/j.1442-2042.1997.tb00144.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9179671-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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