Article
The effect of inhaled glucocorticosteroids in emphysema due to alpha1-antitrypsin deficiency.
Respiratory medicine - 1 May 1997
Wilcke J T, Dirksen A
Abstract excerpt
Despite the success of inhaled steroids in controlling asthma, the benefit in patients with chronic obstructive pulmonary disease (COPD) remains controversial. Five subjects with moderate to severe emphysema due to alpha 1-antitrypsin deficiency (phenotype PiZ) were followed with daily home spirometry in a 2 x 8 weeks, randomized double-blind, placebo-controlled, crossover study of inhaled budesonide 0.8 mg...
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