Characterization of endonuclease III (nth) and endonuclease VIII (nei) mutants of Escherichia coli K-12.

doi:10.1128/jb.179.11.3783-3785.1997

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Article

Characterization of endonuclease III (nth) and endonuclease VIII (nei) mutants of Escherichia coli K-12.

Journal of bacteriology - 1 Jun 1997

Saito Y, Uraki F, Nakajima S, Asaeda A, Ono K, Kubo K, Yamamoto K

Abstract excerpt

The nth and nei genes of Escherichia coli affect the production of endonuclease III and endonuclease VIII, respectively, glycosylases/apurinic lyases that attack DNA damaged by oxidizing agents. Here, we provide evidence that oxidative lethal lesions are repaired by both endonuclease III and endo...

Topics

Cloning, Molecular
Deoxyribonuclease (Pyrimidine Dimer)
Endodeoxyribonucleases
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial
Molecular Sequence Data
Mutation

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