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Article

A new type of hemophore-dependent heme acquisition system of Serratia marcescens reconstituted in Escherichia coli.

Journal of bacteriology - 1 Jun 1997

Ghigo J M, Létoffé S, Wandersman C

Abstract excerpt

The utilization by Serratia marcescens of heme bound to hemoglobin requires HasA, an extracellular heme-binding protein. This unique heme acquisition system was studied in an Escherichia coli hemA mutant that was a heme auxotroph. We identified a 92-kDa iron-regulated S. marcescens outer membrane protein, HasR, which alone enabled the E. coli hemA mutant to grow on heme or hemoglobin as a porphyrin source. The...

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Identifiers

PMID: 9171402
DOI: 10.1128/jb.179.11.3572-3579.1997
PMCID: PMC179150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A new type of hemophore-dependent heme acquisition system of Serratia marcescens reconstituted in Escherichia coli.PMID 9171402Read ↗

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