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Article

Control of heme homeostasis in Corynebacterium glutamicum by the two-component system HrrSA.

Journal of bacteriology - 1 Mar 2011

Frunzke Julia, Gätgens Cornelia, Brocker Melanie, Bott Michael

Abstract excerpt

The response regulator HrrA of the HrrSA two-component system (previously named CgtSR11) was recently found to be repressed by the global iron-dependent regulator DtxR in Corynebacterium glutamicum. Here, we provide evidence that HrrA mediates heme-dependent gene regulation in this nonpathogenic soil bacterium. Growth experiments and DNA microarray analysis revealed that C. glutamicum is able to use hemin as an...

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Identifiers

PMID: 21217007
DOI: 10.1128/JB.01130-10
PMCID: PMC3067591

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Control of heme homeostasis in Corynebacterium glutamicum by the two-component system HrrSA.PMID 21217007Read ↗

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