Article
Angiotensin-converting enzyme gene polymorphism is not associated with coronary atherosclerosis and myocardial infarction in a sample of Italian patients.
European journal of clinical investigation - 1 Jun 1998
Arca M, Pannitteri G, Campagna F, Candeloro A, Montali A, Cantini R, Seccareccia F, Campa P P, Marino B, Ricci G
Abstract excerpt
BACKGROUND: The deletion (D) allele of the angiotensin-converting enzyme (ACE) gene has been proposed as a genetic marker of the risk of ischaemic heart disease. However, the relationships between ACE genotypes, the development of coronary atherosclerosis and the occurrence of major coronary events are still controversial. METHODS: To investigate whether the ACE I/D (insertion/deletion) polymorphism predicts the...
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