Article
Is primary biliary cirrhosis a model autoimmune disease?
Autoimmunity reviews - 1 Jun 2004
Ichiki Yasunori, Shimoda Shinji, Ishibashi Hiromi, Gershwin M Eric
Abstract excerpt
Primary biliary cirrhosis (PBC) has been coined a model autoimmune disease. In fact, it does share many similarities with other autoimmune diseases, but there are striking differences that illustrate the uniqueness of the immunopathology. Firstly, similar to other autoimmune diseases, there is an intense humoral and cellular response to an intracytoplasmic antigen. There is also an overlap of the epitopes...
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