Article
Roles of rDNA spacer and transcription unit-sequences in X-Y meiotic chromosome pairing in Drosophila melanogaster males.
Chromosoma - 1 Jun 1997
Ren X, Eisenhour L, Hong C, Lee Y, McKee B D
Abstract excerpt
Meiotic pairing of the X and Y chromosomes in Drosophila melanogaster males is mediated by the rDNA repeats, which are present in two tandem clusters, one in the centric X heterochromatin and the other near the base of the short arm of the Y chromosome. Deletion of the X chromosomal rDNA cluster disrupts X-Y pairing and causes high frequences of X-Y nondisjunction. Pairing can be partly restored by insertions of...
Topics
- Animals
- Animals, Genetically Modified
- Blotting, Southern
- Cloning, Molecular
- DNA Transposable Elements
- DNA, Ribosomal
- Drosophila melanogaster
- Female
- Gene Rearrangement
- Genetic Variation
- Male
- Meiosis
- Promoter Regions, Genetic
- RNA, Ribosomal, 28S