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Parvovirus Minute Virus of Mice Induces a DNA Damage Response That Facilitates Viral Replication

7 Oct 2010

Abstract excerpt

Infection by DNA viruses can elicit DNA damage responses (DDRs) in host cells. In some cases the DDR presents a block to viral replication that must be overcome, and in other cases the infecting agent exploits the DDR to facilitate replication. We find that low multiplicity infection with the autonomous parvovirus minute virus of mice (MVM) results in the activation of a DDR, characterized by the phosphorylation...

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PMID: 20949077
DOI: 10.1371/journal.ppat.1001141

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