Article
Phenotypic features of BHK-21 cells used for production of foot-and-mouth disease vaccine.
Biologicals : journal of the International Association of Biological Standardization - 1 Mar 1997
Amadori M, Volpe G, Defilippi P, Berneri C
Abstract excerpt
BHK-21 c13 monolayer and suspension cells were investigated with regard to some phenotypic features which could bear on the quality of foot-and-mouth disease virus (FMDV) antigen produced in them. Despite good viability, suspension cells differed from monolayer cells in fundamental features of susceptibility to FMDV. Most important, FMD virus particles grown in suspension cells at high passage levels were shown...
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