Article
Induction of immunotolerance in rats by intratesticular administration of an eicosapeptide of bovine S-antigen.
Autoimmunity - 1 Jan 1996
Ren J, Singh A K, Gregerson D S, Shichi H
Abstract excerpt
Immunization of albino LEW rats with a retinal soluble antigen (S-antigen) induces experimental autoimmune uveoretinitis (EAU) which shows clinical features resembling those of human uveitis. Several uveitogenic epitopes have been identified in the antigen. This study reports that an intratesticular injection of low doses of a uveitogenic eicosapeptide (P343-362) of S-antigen prior to immunization with the same...
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