Article
Participation of non-major histocompatibility antigen complex gene in experimental autoimmune uveitis.
Japanese journal of ophthalmology - 1 Jan 1995
Yoshikawa K, Hirose S, Sasamoto Y, Kotake S, Matsuda H
Abstract excerpt
It is known that the susceptibility to experimental autoimmune uveitis (EAU) is controlled by both major histocompatibility antigen complex (MHC) and non-MHC genes. In this report, we studied the role of non-MHC genes in the induction of EAU. LEW, WKAH, (LEW x WKAH)F1, and (LEW x WKAH)F2 rats were examined to determine the incidence and severity of EAU induced by immunization with bovine S-antigen (S-Ag). We...
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