Neutralizing TNF-alpha activity modulates T-cell phenotype and function in experimental autoimmune uveoretinitis.

doi:10.1006/jaut.1998.0197

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Article

Neutralizing TNF-alpha activity modulates T-cell phenotype and function in experimental autoimmune uveoretinitis.

Journal of autoimmunity - 1 Jun 1998

Dick A D, Duncan L, Hale G, Waldmann H, Isaacs J

Abstract excerpt

Inhibiting TNF-alpha activity prevents tissue destruction without inhibiting retinal T cell infiltration in experimental autoimmune uveoretinitis (EAU) in Lewis rats. To further determine the role of TNF-alpha in autoimmune uveitis we characterized T cells isolated from retinae after treatment wi...

Topics

Animals
Anterior Chamber
Autoimmune Diseases
Biomarkers
Cell Division
Cell Movement
Female
Immunoconjugates
Immunoglobulin G
Interferon-gamma
Interleukin-4
Neutralization Tests
Phenotype
Rats
Rats, Inbred Lew
Receptors, Tumor Necrosis Factor
Retinitis
T-Lymphocyte Subsets

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PMID: 9693974
DOI: 10.1006/jaut.1998.0197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9693974-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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