A novel DR beta 1*03 allele identified by polymerase chain reaction-restriction fragment length polymorphism.

Abstract excerpt

This report describes a new MHC class II allele, HLA-DR beta 1*0306, discovered in a 31-year-old Norwegian male. The allele typed serologically as DRw52 (DR3) and amplified in PCR using DR52-associated group primers. This product could not be identified using established restriction digests, howe...

Topics

• Adult
• Alleles
• Base Sequence
• Codon
• Genes, MHC Class II
• HLA-DR Antigens
• HLA-DRB1 Chains
• Humans
• Male
• Molecular Sequence Data
• Point Mutation
• Polymerase Chain Reaction
• Polymorphism, Restriction Fragment Length
• Sequence Alignment
• Sequence Homology, Nucleic Acid