Article
[Mechanisms for the development of quinolone resistance].
Nihon rinsho. Japanese journal of clinical medicine - 1 May 1997
Kojima M
Abstract excerpt
New fluoroquinolones have potent and broad antimicrobial activity and spectra, respectively, against gram-positive and -negative bacteria including P. aeruginosa. As a result of their frequent use, bacterial resistance to the quinolones has gradually developed and limited their therapeutic efficacy in infections, especially, with P. aeruginosa, S. pneumoniae, S. aureus (especially MRSA), and N. gonorrhoeae....
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