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Article

A conditional sterol esterification defect in yeast having either a sec1 or sec5 mutation in the secretory pathway.

Yeast (Chichester, England) - 1 Apr 1997

Tomeo M E, Palermo L M, Tove S, Parks L W

Abstract excerpt

Two temperature-conditional secretory mutations, sec1 and sec5, cause the accumulation of post-Golgi vesicles when strains containing these mutations are grown at 37 degrees C. In addition to accumulating vesicles, the mutants do not esterify free sterol on rich media at the restrictive temperature. It is the high level of inositol in the media that causes this condition in the yeast Saccharomyces cerevisiae, not...

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PMID: 9153755
DOI: 10.1002/(SICI)1097-0061(199704)13:5<449::AID-YEA99>3.0.CO;2-A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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