A conditional sterol esterification defect in yeast having either a sec1 or sec5 mutation in the secretory pathway.

doi:10.1002/(SICI)1097-0061(199704)13:5<449::AID-YEA99>3.0.CO;2-A

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Article

A conditional sterol esterification defect in yeast having either a sec1 or sec5 mutation in the secretory pathway.

Yeast (Chichester, England) - 1 Apr 1997

Tomeo M E, Palermo L M, Tove S, Parks L W

Abstract excerpt

Two temperature-conditional secretory mutations, sec1 and sec5, cause the accumulation of post-Golgi vesicles when strains containing these mutations are grown at 37 degrees C. In addition to accumulating vesicles, the mutants do not esterify free sterol on rich media at the restrictive temperatu...

Topics

Esterification
Fatty Acids
Fungal Proteins
Golgi Apparatus
Inositol
Intracellular Membranes
Mutation
Phospholipids
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Sterols
Suppression, Genetic
Temperature

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