Article
Functional analysis of human RPS14 null alleles.
Journal of cell science - 1 Apr 1997
Martin-Nieto J, Roufa D J
Abstract excerpt
Previously we described a large collection of cloned human DNAs that encode chemically defined missense mutations within the ribosomal protein S14 sequence. We determined that biologically inactive (i.e. null) alleles resulted primarily from point mutations targeted to two internal segments of the S14-coding sequence and designated these functionally critical regions as domains B and D. Further, we inferred that...
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