Article
Inactivation of the Rps4 gene on the mouse X chromosome.
Genomics - 1 Dec 1991
Zinn A R, Bressler S L, Beer-Romero P, Adler D A, Chapman V M, Page D C, Disteche C M
Abstract excerpt
The human RPS4X and RPS4Y genes, located on the X and Y chromosomes, appear to encode isoforms of ribosomal protein S4. Haploinsufficiency of these genes may contribute to the human phenotype known as Turner syndrome. Although RPS4X maps near the X-inactivation center, the gene is expressed on inactive human X chromosomes. We cloned Rps4, the mouse homolog of RPS4X. Exploiting allelic variation in Rps4, we...
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