Inactivation of the Rps4 gene on the mouse X chromosome.

doi:10.1016/0888-7543(91)90037-f

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Article

Inactivation of the Rps4 gene on the mouse X chromosome.

Genomics - 1 Dec 1991

Zinn A R, Bressler S L, Beer-Romero P, Adler D A, Chapman V M, Page D C, Disteche C M

Abstract excerpt

The human RPS4X and RPS4Y genes, located on the X and Y chromosomes, appear to encode isoforms of ribosomal protein S4. Haploinsufficiency of these genes may contribute to the human phenotype known as Turner syndrome. Although RPS4X maps near the X-inactivation center, the gene is expressed on inactive human X chromosomes. We cloned Rps4, the mouse homolog of RPS4X. Exploiting allelic variation in Rps4, we...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
DNA
Dosage Compensation, Genetic
Female
Gene Expression Regulation
Genetic Variation
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Molecular Sequence Data

Polymerase Chain Reaction

Ribosomal Proteins

Translocation, Genetic

X Chromosome

Source

Open in PubMed

Identifiers

PMID: 1783379
DOI: 10.1016/0888-7543(91)90037-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1783379-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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