Article
Determination of hepatitis C virus genotype by direct sequence analysis of products generated with the Amplicor HCV test.
Journal of clinical microbiology - 1 Aug 1999
Germer J J, Rys P N, Thorvilson J N, Persing D H
Abstract excerpt
Consistent with other members of the family Flaviviridae, hepatitis C virus (HCV) demonstrates a high degree of sequence variation throughout the coding regions of its genome. However, there is a high degree of sequence conservation found within the 5' untranslated region (UTR) of the genome, making this region a target of choice for most nucleic acid amplification-based detection assays. In this study, the...
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