The role of MHC class I heterodimer expression in mouse ankylosing enthesopathy.

doi:10.1007/s002510050239

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Article

The role of MHC class I heterodimer expression in mouse ankylosing enthesopathy.

Immunogenetics - 1 Jan 1997

Weinreich S S, Hoebe-Hewryk B, van der Horst A R, Boog C J, Ivanyi P

Abstract excerpt

Ankylosing enthesopathy (ANKENT) is a spontaneous mouse joint disease with strikingly similar pathology to human HLA-B27-associated enthesopathies such as ankylosing spondylitis. In C57Bl/10 mice, transgenic HLA-B*2702 as well as H2 genes have been shown to be relative risk factors for ANKENT. To...

Topics

Animals
Ankylosis
Dimerization
Genotype
H-2 Antigens
HLA-B27 Antigen
Histocompatibility Antigens Class I
Humans
Immunophenotyping
Incidence
Mice
Mice, Knockout
Mice, Transgenic
T-Lymphocyte Subsets
Transgenes
beta 2-Microglobulin

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