Article
The role of MHC class I heterodimer expression in mouse ankylosing enthesopathy.
Immunogenetics - 1 Jan 1997
Weinreich S S, Hoebe-Hewryk B, van der Horst A R, Boog C J, Ivanyi P
Abstract excerpt
Ankylosing enthesopathy (ANKENT) is a spontaneous mouse joint disease with strikingly similar pathology to human HLA-B27-associated enthesopathies such as ankylosing spondylitis. In C57Bl/10 mice, transgenic HLA-B*2702 as well as H2 genes have been shown to be relative risk factors for ANKENT. To investigate the role of major histocompatibility complex (MHC) class I expression in disease pathogenesis, ANKENT...
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