Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer.

The New England journal of medicine - 15 May 1997

Couch F J, DeShano M L, Blackwood M A, Calzone K, Stopfer J, Campeau L, Ganguly A, Rebbeck T, Weber B L

Abstract excerpt

BACKGROUND: To define the incidence of BRCA1 mutations among patients seen in clinics that evaluate the risk of breast cancer, we analyzed DNA samples from women seen in this setting and constructed probability tables to provide estimates of the likelihood of finding a BRCA1 mutation in individual families. METHODS: Clinical information, family histories, and blood for DNA analysis were obtained from 263 women...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Analysis of Variance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to DNA Mutational Analysis

Share to Genetic Linkage

Share to Incidence

Share to Mutation

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 9145677
DOI: 10.1056/NEJM199705153362002

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer.PMID 9145677Read ↗

BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing.Semantic proximity Read ↗

Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program.Semantic proximity Read ↗

BRCA1 and BRCA2 gene mutations and risk of breast cancer. Public health perspectives.Semantic proximity Read ↗

Characterization of BRCA1 and BRCA2 mutations in a large United States sample.Semantic proximity Read ↗

Frequency of breast cancer attributable to BRCA1 in a population-based series of American women.Semantic proximity Read ↗

Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals.Semantic proximity Read ↗

BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing for hereditary breast-ovarian cancer.Semantic proximity Read ↗

Cancer Incidence in BRCA1 mutation carriers.Semantic proximity Read ↗

BRCA1 Mutations and Breast Cancer in the General PopulationSemantic proximity Read ↗

Probability of carrying a mutation of breast-ovarian cancer gene BRCA1 based on family history.Semantic proximity Read ↗

Hereditary breast and ovarian cancer due to mutations in BRCA1 and BRCA2.Semantic proximity Read ↗

Cancer Incidence in First- and Second-Degree Relatives of BRCA1 and BRCA2 Mutation Carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.