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Article

BRCA1 Mutations and Breast Cancer in the General Population

25 Mar 1998

Abstract excerpt

CONTEXT: Studies of high-risk families with multiple early-onset cases of breast cancer have been useful for assessing the type and spectrum of germline mutations on the BRCA1 gene, but do not provide guidance to women with modest family history profiles. Thus, studies of women from the general population are needed to determine the BRCA1 mutation frequency in women perceived to be at high risk, and to develop...

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PMID: 9544766
DOI: 10.1001/jama.279.12.922

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