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Article

Amino acid variants in the human leptin receptor: lack of association to juvenile onset obesity.

Biochemical and biophysical research communications - 7 Apr 1997

Echwald S M, Sørensen T D, Sørensen T I, Tybjaerg-Hansen A, Andersen T, Chung W K, Leibel R L, Pedersen O

Abstract excerpt

The recently described putative lipostat system mediated in part by leptin and its hypothalamic receptor provides logical candidate genes for the molecular basis of inherited obesity in humans on the basis of the occurrence of profound obesity observed in obese and diabetic mice, in which the genes for leptin or its receptor, respectively, are mutated. In this study we tested the hypothesis that juvenile onset...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9144432
DOI: 10.1006/bbrc.1997.6430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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