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Glial TGFβ activity promotes axon survival in peripheral nerves

2021-09-03

Abstract excerpt

Axons can represent the majority of the volume of a neuron and are energetically very demanding. Specialized glia ensheathe axons and are believed to support axon function and maintenance throughout life, but molecular details of glia-neuron support mechanisms remain poorly defined. Here we identify a collection of secreted and transmembrane genes that are required in glia for long-term axon survival in vivo . We...

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Literature Corpus work
d280c1ac-33c6-5f97-9293-1f036339f276
DOI
10.1101/2021.09.02.458753
Open publication

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Glial TGFβ activity promotes axon survival in peripheral nervesDOI 10.1101/2021.09.02.458753
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