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Article

Estimation of effects of quantitative trait loci in large complex pedigrees.

Genetics - 1 May 1997

Meuwissen T H, Goddard M E

Abstract excerpt

A method was derived to estimate effects of quantitative trait loci (QTL) using incomplete genotype information in large outbreeding populations with complex pedigrees. The method accounts for background genes by estimating polygenic effects. The basic equations used are very similar to the usual linear mixed model equations for polygenic models, and segregation analysis was used to estimate the probabilities of...

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PMID: 9136029
DOI: 10.1093/genetics/146.1.409
PMCID: PMC1207956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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