Article
Detecting the undetected: estimating the total number of loci underlying a quantitative trait.
Genetics - 1 Dec 2000
Otto S P, Jones C D
Abstract excerpt
Recent studies have begun to reveal the genes underlying quantitative trait differences between closely related populations. Not all quantitative trait loci (QTL) are, however, equally likely to be detected. QTL studies involve a limited number of crosses, individuals, and genetic markers and, as a result, often have little power to detect genetic factors of small to moderate effects. In this article, we develop...
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