Article
HLA class II genotyping of sarcoidosis patients in Hokkaido by PCR-RFLP.
Japanese journal of ophthalmology - 1 Jan 1996
Ishihara M, Inoko H, Suzuki K, Ono H, Hiraga Y, Ando H, Naruse T, Ishida T, Ohno S
Abstract excerpt
To confirm the significant association of sarcoidosis with HLA-DR5, -DR6, and -DR8 associated DRB1 alleles, in sarcoidosis patients from the eastern Japan (Kanto) area found in our previous study, we used HLA class II genotyping of patients in another region-Hokkaido, in northern Japan. The annual incidence of sarcoidosis in Hokkaido is about three times that of eastern Japan, and Hokkaido has one of the world's...
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