Article
Human leukocyte antigen-A, -B, and -DRB1 alleles and sarcoidosis in Chinese Han subjects.
Human immunology - 1 Jul 2011
Zhou Ying, Shen Li, Zhang Yuan, Jiang Dianhua, Li Huiping
Abstract excerpt
Human leukocyte antigens (HLA) play a key role in antigen presentation. HLA genes, especially HLA-A, -B, and -DRB1, which are highly polymorphic, have been thought to be candidate loci for the etiology of sarcoidosis. This study aimed to assess the association between the polymorphism of HLA-A, -B, and -DRB1 alleles and sarcoidosis in Chinese Han subjects. Genomic DNA was extracted from 131 patients with...
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