Molecular genetic studies of HLA class II alleles in sarcoidosis

doi:10.1111/j.1399-0039.1994.tb02331.x

Article

Molecular genetic studies of HLA class II alleles in sarcoidosis

1 Apr 1994

Abstract excerpt

Previous HLA serological studies showed positive associations of the DR52 antigen, the DR52-associated antigens (DR3, DR5 and DR6) and the DR8 antigen with sarcoidosis. To investigate the HLA alleles that may contribute to the genetic susceptibility to sarcoidosis at the DNA level, HLA-DRB1, -DRB3, -DQA1 and DQB1 genotyping using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)...

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