Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variable immortalizing potential and frequent virus latency in blood-derived T-cell clones infected with human T-cell leukemia virus type I.

Blood - 1 May 1997

Richardson J H, Höllsberg P, Windhagen A, Child L A, Hafler D A, Lever A M

Abstract excerpt

Human T-cell leukemia virus type I (HTLV-I)-infected T cells expanded in vitro by single-cell cloning provide a unique system for investigating virus-cell interactions in nonimmortalized T cells. By analysis of clones generated randomly from the blood of virus carriers, we confirm that CD4 T cells are the major reservoir of HTLV-I in vivo and show that most infected cells contain a single integrated provirus....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Southern
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Phenotype

Share to Polymerase Chain Reaction

Share to RNA, Messenger

Share to T-Lymphocytes

Share to Transcription, Genetic

Source

Identifiers

PMID: 9129036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variable immortalizing potential and frequent virus latency in blood-derived T-cell clones infected with human T-cell leukemia virus type I.PMID 9129036Read ↗

The molecular and phenotypic signature of human T-cell lymphotropic virus type 1 infected clones and their malignant potentialSemantic proximity Read ↗

Clonal expansion of infected cells: a way of life for HTLV-I.Semantic proximity Read ↗

Persistent Epstein‐Barr virus infection in a human T‐cell line: unique program of latent virus expression.Semantic proximity Read ↗

The relative contributions of infectious and mitotic spread to HTLV-1 persistenceSemantic proximity Read ↗

Virus inactivation in a proportion of human T-cell leukaemia virus type I-infected T-cell clones arises through naturally occurring mutations.Semantic proximity Read ↗

Clonal expansion of HTLV-1 infected cells depends on the CD4 versus CD8 phenotype.Semantic proximity Read ↗

HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated ProvirusSemantic proximity Read ↗

Different human resting memory CD4+ T cell subsets show similar low inducibility of latent HIV-1 proviruses.Semantic proximity Read ↗

Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress–induced apoptosisSemantic proximity Read ↗

HIV-1 latency in actively dividing human T cell linesSemantic proximity Read ↗

Single-cell heterogeneity and cell-cycle-related viral gene bursts in the human leukaemia virus HTLV-1Semantic proximity Read ↗

Persistently human immunodeficiency virus type 1-infected T cell clone expressing only doubly spliced mRNA exhibits reduced cell surface CD4 expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.