Article
Ontogeny of membrane cofactor protein: phenotypic divergence in the fetal heart.
Lupus - 1 Aug 1995
Gorelick A, Oglesby T, Rashbaum W, Atkinson J, Buyon J P
Abstract excerpt
Human adult cells are protected from complement-induced damage in part by membrane cofactor protein (MCP, CD46). To examine fetal characteristics which might influence autoantibody-mediated diseases acquired in utero, such as heart block in neonatal lupus, the tissue expression of MCP was studied. Using a high ratio of acrylamide:bisacrylamide, immunoblots of tissues from six fetuses (aged 19-24 weeks) probed...
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