Ontogeny of membrane cofactor protein: phenotypic divergence in the fetal heart.

doi:10.1177/096120339500400410

Back to search

Article

Ontogeny of membrane cofactor protein: phenotypic divergence in the fetal heart.

Lupus - 1 Aug 1995

Gorelick A, Oglesby T, Rashbaum W, Atkinson J, Buyon J P

Abstract excerpt

Human adult cells are protected from complement-induced damage in part by membrane cofactor protein (MCP, CD46). To examine fetal characteristics which might influence autoantibody-mediated diseases acquired in utero, such as heart block in neonatal lupus, the tissue expression of MCP was studied...

Topics

Antigens, CD
Fetus
Gestational Age
Humans
Immunoblotting
Lupus Erythematosus, Systemic
Membrane Cofactor Protein
Membrane Glycoproteins
Myocardium
Phenotype
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.