Article
Desensitization of the P2X(2) receptor controlled by alternative splicing.
FEBS letters - 10 Mar 1997
Brändle U, Spielmanns P, Osteroth R, Sim J, Surprenant A, Buell G, Ruppersberg J P, Plinkert P K, Zenner H P, Glowatzki E
Abstract excerpt
P2X receptors are ion channels gated by extracellular ATP. We report here cloning of a P2X(2) receptor splice variant (P2X(2-2)) carrying a 207 bp deletion in the intracellular C-terminus and the analysis of the corresponding genomic structure of the P2X(2) gene. P2X(2-2) is as highly expressed a...
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